Serine Protease

Mechanism-based inactivation of human leukocyte elastase via an enzyme-induced sulfonamide fragmentation process

Enzyme Inhibitors / Humans / Drug Design / Fragmentation / Enzyme / Active site / Time Dependent / Substrate Specificity / Serine Protease / Methyl Ester / Biochemistry and cell biology / Active site / Time Dependent / Substrate Specificity / Serine Protease / Methyl Ester / Biochemistry and cell biology

Regulated Degradation of an Endoplasmic Reticulum Membrane Protein in a Tubular Lysosome in Leishmania mexicana

Electron Microscopy / Molecular Biology / Immunohistochemistry / Confocal Microscopy / Biological Sciences / Humans / Animals / Endoplasmic Reticulum / Cell Fractionation / Microtubules / Green Fluorescent Protein / Enzyme / Membrane Protein / Subcellular Fractions / Lysosomes / Golgi Apparatus / Cell Surface Markers / Hydrogen-Ion Concentration / Serine Protease / Protein Transport / Immunoblotting / Humans / Animals / Endoplasmic Reticulum / Cell Fractionation / Microtubules / Green Fluorescent Protein / Enzyme / Membrane Protein / Subcellular Fractions / Lysosomes / Golgi Apparatus / Cell Surface Markers / Hydrogen-Ion Concentration / Serine Protease / Protein Transport / Immunoblotting

Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana

Electron Microscopy / Molecular Biology / Immunohistochemistry / Confocal Microscopy / Biological Sciences / Humans / Animals / Endoplasmic Reticulum / Cell Fractionation / Microtubules / Green Fluorescent Protein / Enzyme / Membrane Protein / Subcellular Fractions / Lysosomes / Golgi Apparatus / Cell Surface Markers / Hydrogen-Ion Concentration / Serine Protease / Protein Transport / Immunoblotting / Humans / Animals / Endoplasmic Reticulum / Cell Fractionation / Microtubules / Green Fluorescent Protein / Enzyme / Membrane Protein / Subcellular Fractions / Lysosomes / Golgi Apparatus / Cell Surface Markers / Hydrogen-Ion Concentration / Serine Protease / Protein Transport / Immunoblotting

Peptide and amino acid transport in Streptococcus bovis

Multidisciplinary / Peptides / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Applied Microbiology and Biotechnology / Amino Acids / Streptococcus / Amino Acid Profile / Amino Acid Sequence / Sodium Dodecyl Sulphate / Polyacrylamide Gel Electrophoresis / Hydrolysis / Serine Protease / Proteolytic activity / Molecular Sequence Data / Streptococcus / Amino Acid Profile / Amino Acid Sequence / Sodium Dodecyl Sulphate / Polyacrylamide Gel Electrophoresis / Hydrolysis / Serine Protease / Proteolytic activity / Molecular Sequence Data

Design and characterization of a novel cellular prion-derived quenched fluorimetric substrate of α-secretase

Membrane Proteins / Protein Engineering / Cell line / Humans / Kidney / Mice / Animals / Biochemical / Prion disease / Substrate Specificity / Amino Acid Profile / Transfection / Human Fibroblasts / Serine Protease / Fluorometry / Biochemistry and cell biology / Prion Protein / Mice / Animals / Biochemical / Prion disease / Substrate Specificity / Amino Acid Profile / Transfection / Human Fibroblasts / Serine Protease / Fluorometry / Biochemistry and cell biology / Prion Protein

Production of extracellular enzymes by different isolates of Pochonia chlamydosporia

Microbiology / Plant Biology / Olive Oil / Animals / Enzyme / Specific Activity / Nematoda / Enzyme activity / Culture Media / Serine Protease / Extracellular Space / Rank Correlation / Glycosyl Hydrolases / Specific Activity / Nematoda / Enzyme activity / Culture Media / Serine Protease / Extracellular Space / Rank Correlation / Glycosyl Hydrolases

Phosphonic pseudopeptides as human neutrophil elastase inhibitors—a combinatorial approach

Organic Chemistry / Cystic Fibrosis / Rheumatoid Arthritis / Single molecule / Humans / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin

Lesional elastase activity in psoriasis

Clinical Sciences / Enzymatic Activity / Serine Protease

Phase-Variable Expression of an Operon Encoding Extracellular Alkaline Protease, a Serine Protease Homolog, and Lipase in Pseudomonas brassicacearum

Bacteriology / Membrane Proteins / Biological Sciences / Escherichia coli / Pseudomonas / Membrane transport proteins / Recombinant Proteins / Serine Protease / Lipase / Membrane transport proteins / Recombinant Proteins / Serine Protease / Lipase

Human Leukocyte Elastase Induces Keratinocyte Proliferation In Vitro and In Vivo

Cell Division / Cell line / Humans / Keratinocytes / Mice / Animals / Clinical Sciences / Protease Inhibitors / INVESTIGATIVE / Serine Protease / Animals / Clinical Sciences / Protease Inhibitors / INVESTIGATIVE / Serine Protease

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

Genetics / Mass Spectrometry / Molecular / real time PCR / Tissue culture / Amyloid Beta / Enzyme / Clinical Sciences / Amino Acid Profile / Serine Protease / Neurosciences / Senile Plaques / Amyloid Beta / Enzyme / Clinical Sciences / Amino Acid Profile / Serine Protease / Neurosciences / Senile Plaques

Subcellular localization of an extracellular serine protease in Leishmania (Leishmania) amazonensis

Microbiology / Parasitology / Medical Microbiology / Animals / Host-parasite interactions / Affinity chromatography / Enzyme / Subcellular Localization / Veterinary Sciences / Lysosomes / Enzymatic Activity / Serine Protease / Immunoblotting / Affinity chromatography / Enzyme / Subcellular Localization / Veterinary Sciences / Lysosomes / Enzymatic Activity / Serine Protease / Immunoblotting

Developmental pattern of plasminogen activator activity in chick optic lobe

Cognitive Science / Developmental neuroscience / Morphogenesis / Linear models / Neural Development / Molecular typing / Animals / Temporal Correlation / Neural plasticity / Neuronal Migration / Serine Protease / Neurosciences / Plasminogen Activator / Neurite Outgrowth / Molecular typing / Animals / Temporal Correlation / Neural plasticity / Neuronal Migration / Serine Protease / Neurosciences / Plasminogen Activator / Neurite Outgrowth

Phosphonic pseudopeptides as human neutrophil elastase inhibitors—a combinatorial approach

Organic Chemistry / Cystic Fibrosis / Rheumatoid Arthritis / Single molecule / Humans / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin

Antibodies as defensive enzymes

Innate immunity / Protein Structure and Function / Enzymes / Humans / Autoimmune Disease / Mice / Animals / Hiv Infection / Enzyme / Clinical Sciences / Amino Acid Sequence / Serine Protease / Catalytic Activity / Immunoglobulin / Mice / Animals / Hiv Infection / Enzyme / Clinical Sciences / Amino Acid Sequence / Serine Protease / Catalytic Activity / Immunoglobulin

Ketopyrrolidines and ketoazetidines as potent dipeptidyl peptidase IV (DPP IV) inhibitors

Organic Chemistry / Animals / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Serine Protease / Molecular Structure / Serine Protease / Molecular Structure

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